Comparison of NGS technologies – just a waste of time?
As already mentioned in our latest blog post Michael Quail and his team from the Sanger Institute published a comparison of the Ion Torrent PGM, the PacBio RS system and the Illumina MiSeq (BMC Genomics). This study and all the others performed recently couldn’t determine one clear winner as each system has its own advantages.
But really interesting are now the statements of the spokespersons from the different companies in a recent article from Julia Karow in GenomeWeb. They all agree on the same thing: the data collected in the publication have been true in 2011, but are outdated by now since a lot of effort is put into innovation. Every instrument performs a lot better now. So what is our conclusion? That comparisons for NGS technologies are just a waste of time? For the Sanger institute it means that they invested in 3 new MiSeq’s since the Illumina pipeline is already available. For me, these comparisons are also valuable for all other institutes. Although maybe outdated, they highlight the strength and weaknesses of each technology and help to decide where to invest thousands of dollars. What do you think?