Archive | August 19, 2011

Next Generation Sequencing: Is There New Hope For Patients With Rare Diseases?

Some new studies published online in Science Translational Medicine  ( Sirota et al. > and Dudley et al. > ) demonstrate the potential of genomics to find new applications for existing drugs ( GenomeWeb >). They detected 53 significant drug-disease interactions. In one case they could find evidence that the ulcer drug cimetidine might be effective against lung cancer.

This gives new hope for effective treatment of rare diseases, where new potential orphan drugs are not available.

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